Question for Physiotherapists
Syndesmosis Injury
Welcome to Question for Physiotherapists November 2025. This month Dr John Negrine discusses syndesmosis injury.
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QUESTION | Are we overthinking Syndesmosis Injury?
ANSWER | I pay tribute to my friend and colleague Harvinder Bedi in Melbourne who gave the best talk at the last combined meeting of the Australian and New Zealand Foot and ankle societies on this very subject.
When watching rugby league on the television and the commentator diagnoses a syndesmosis injury it’s time to revisit the so called “high ankle sprain”!
The syndesmosis anatomy is well known to you, the anterior and posterior inferior tibiofibular ligaments as well as the interosseous membrane.
The mechanism of injury typically involves abduction, dorsiflexion and external rotation.
Quick refresher on the grades:
I Partial injury to AITFL, IOM and PITFL intact – considered stable
II Complete injury to AITFL, partial IOM, PITFL intact – may or not be unstable
III Complete injury to AITFL, IOM and PITFL – probably unstable
A good MRI scan with an experienced radiologist will readily diagnose injuries to these ligaments….it will not however diagnose instability and that is (perhaps) the key.
Few would argue that a complete rupture of all three components of the syndesmosis with separation on plain weight bearing films would require stabilisation.
There is however controversy regarding the rupture of the AITFL and interosseous membrane with no demonstrable instability on plain films….the Grade II injury.
James Calder in 2016 (arthroscopy 32:4, 643, 2016) stated that a deltoid ligament tear, frank diastasis on weightbearing films and a positive squeeze test were all good indicators of instability. He correlated this with MRI scans and findings at arthroscopy (3mm of widening was considered unstable.) All his patients were professional athletes.
If stable and managed non-operatively return to sport took 45 days, if unstable and treated surgically 64 days.
Naturally in the professional athlete the fastest return to sport is the key so early arthroscopy is often performed in this country……
Harvinder Bedi postulates (and I agree) that waiting a few weeks in the non professional athlete will do no harm and avoid unnecessary surgery. He also postulates that many grade II and grade III injuries can be managed non-operatively.
What we don’t know is the natural history of what we are seeing on MRI scan. My suspicion is that they don’t all go onto chronic disability and arthritis even in the grade III injuries. Here I am talking about the pure ligamentous injury not the fracture dislocations.

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Previous Question for Physiotherapists:
| Dec-2020 | Wrist Ganglions | Dr Kwan Yeoh |
| Oct/Nov-2020 | Medial Meniscal Root Tears | Dr Doron Sher |
| Sep-2020 | Lumbar Stress Fractures | Dr Paul Annett |
| Aug-2020 | Frailty and Healthy Ageing | Dr John Best |
| Jul-2020 | Thumb – Collateral Ligament Tear | Dr Kwan Yeoh |
| Jun-2020 | Shoulder Instability | Dr Doron Sher |
| May-2020 | Hallux Rigidus | Dr John Negrine |
| Mar/Apr-2020 | Achilles Tendon Ruptures | Dr Todd Gothelf |
| Feb-2020 | Distal Biceps | Dr Doron Sher |
| Nov-2019 | Clavicle Fracture Internal Fixation | Dr Doron Sher |
| Oct-2019 | Femoracetabular Impingement (FAI) | Dr Paul Mason |
| Sep-2019 | Imaging for Acute ACL Injuries | Dr Doron Sher |
| Aug-2019 | Joint Relocation | Dr Paul Annett |
| Jul-2019 | Guyon canal surgery | Dr Kwan Yeoh |
| Jun-2019 | Whats new in ACL reconstruction 2019 | Dr Doron Sher |
| May-2019 | Cuneiform Fracture | Dr Todd Gothelf |
| Apr-2019 | Flexor Tendon Injuries | Dr Kwan Yeoh |
| Mar-2019 | Chronic Exertional Compartment Synd | Dr Paul Annett |
| Feb-2019 | Achilles Tendon Rupture | Dr John Negrine |
| Nov-2018 | Low Back Pain | Dr Paul Mason |
| Sep-2018 | Concussion part 2 | Dr John Best |
| Jul-2018 | Concussion part1 | Dr Paul Annett |
| Jun-2018 | Thessaly & McMurray Test | Dr Doron Sher |
| May-2018 | AC Joint | Dr Doron Sher |
| Apr-2018 | Arthritis of the fingers | Dr Kwan Yeoh |
| Feb-2018 | CLAVICLE fractures | Dr Doron Sher |
| Oct-2017 | ACL Grafts | Dr Doron Sher |
| Sep-2017 | Forefoot pain | Dr John Negrine |
| Aug-2017 | Wrist Ganglion | Dr Kwan Yeoh |
| Jul-2017 | Anterolateral Ligament Reconstruction | Dr Doron Sher |
| Jun-2017 | Scapholunate ligament | Dr Kwan Yeoh |
| Apr-2017 | Knee Brace – ACL Reconstruction | Dr Doron Sher |
| Mar-2017 | Sesamoid fractures | Dr Kwan Yeoh |
| Feb-2017 | Plantar Fasciitis | Dr Todd Gothelf |
| Nov-2016 | Sternoclavicular Joint | Dr Doron Sher |
| Oct-2016 | Proximal Humerus Fractures | Dr David Lieu |
| Sep-2016 | Wrist Fractures | Dr Kwan Yeoh |
| Aug-2016 | Patella Instability | Dr Doron Sher |
| Jul-2016 | Snowboarders ankle | Dr Todd Gothelf |
| May-2016 | Cortisone Injections | Dr Paul Annett |
| Apr-2016 | Shoulder Instability_1 | Dr Ivan Popoff |
| Mar-2016 | Exercise after TKR | Dr Doron Sher |
| Dec-2015 | Scaphoid OA | Dr Kwan Yeoh |
| Nov-2015 | Greater Tuberosity Fractures | Dr Doron Sher |
| Oct-2015 | Stress Fractures | Dr Paul Annett |
| Sep-2015 | Boxers Fractures | Dr Kwan Yeoh |
| Aug 2015 | Resistance Training | Dr John Best |
| July 2015 | LARS Ligament | Dr Ivan Popoff |
| Jun-2015 | Distal Biceps | Dr Doron Sher |
| May-2015 | Latarjet procedure | Dr Jerome Goldberg |
| Apr-2015 | TFCC Questions | Dr Kwan Yeoh |
| Mar-2015 | Acute Ankle Sprains | Dr Todd Gothelf |
| Nov-2014 | PRPP | Dr Paul Annett |
| Oct-2014 | Driving After Surgery | Dr Doron Sher |
| Sep-2014 | Distal Biceps Rupture | Dr Doron Sher |
| Aug-2014 | Ankle Sprain | Dr Todd Gothelf |
| Jun-2014 | Patella Dislocation | Dr Doron Sher |
| May-2014 | Shoulder Instability | Dr Todd Gothelf |
| Apr-2014 | De Quervains | Dr Kwan Yeoh |
| Mar-2014 | Acromio-clavicular joint injuries | Dr Todd Gothelf |
| Feb-2014 | Chronic Knee Pain | Dr Paul Annett |
| Dec-2013 | Foot and Ankle Questions | Dr John Negrine |
| Oct-2013 | Rotator Cuff Repair | Dr Todd Gothelf |
| Sep-2013 | ACL Reconstruction | Dr Doron Sher |
| Jul-2013 | Slipped Upper femoral epiphysis | Dr Rod Pattinson |
| May-2013 | Skiers thumb | Dr Kwan Yeoh |
| Apr-2013 | Bakers_Cyst | Dr Ivan Popoff |
| Mar-2013 | Tibial Osteotomy vs UKR | Dr Doron Sher |
| Feb-2013 | ALIF success rate | Dr Andreas Loefler |
| Jan-2013 | Lisfranc Injuries | Dr Todd Gothelf |
| Nov-2012 | Anterior Spinal Fusions | Dr Andreas Loefler |
| Oct-2012 | MCL Injuries | Dr Doron Sher |
| Sep-2012 | Compartment Syndrome | DrPaul Annett |
| Aug-2012 | Carpal tunnel | Dr Kwan Yeoh |
| July-2012 | Anterior Process Calcaneus Fx | Dr Todd Gothelf |
| Jun-2012 | Tenodesis vs Tenotomy | DrJeromeGoldberg |
| May-2012 | Osteoarthritis in the young active patient | Dr Doron Sher |
| Apr-2012 | Syndesmosis Sprain | Dr Todd Gothelf |
| Mar-2012 | Triangular Fiocartilage Injuries | Dr Kwan Yeoh |
| Jan-2012 | Shoulder Replacement Older Population | Dr Jerome Goldberg |
| Dec-2011 | Wrist Fracture | Dr Kwan Yeoh |
| Nov-2011 | Adductor Tendon Tear | Dr Paul Annett |
| Oct-2011 | Navicular Pain | Dr Todd Gothelf |
| Sep-2011 | OCD Lesion | Dr Doron Sher |
| Aug-2011 | Metal on Metal Hip Replacements | Dr Andreas Loefler |
| July-2011 | Femoral Neck Stress Fract (Pt 2) | Dr John Best |
| Jun-2011 | Femoral Neck Stress Fractures | Dr John Best |
| May-2011 | PCL Injury Part 2 | Dr Doron Sher |
| Apr-2011 | PCL Injury Part 1 | Dr DoronSher |
| Mar-2011 | Prolotherapy Autologous Blood Injections | DrPaul Annett |
| Feb-2011 | Shoulder Impingement | Dr Todd Gothelf |
| Dec-2010 | Does Chondral Grafting Work | DrDoron Sher |
| Nov-2010 | Shoulder Immobilisation-Dislocation | Dr Jerome Goldberg |
| Sep-2010 | SLAP Lesions Stable Shoulder | Dr ToddGothelf |
| Jul-2010 | Ankle Sprains | Dr Todd Gothelf |
| Jun-2010 | Dislocation After THR | Dr Peter Walker |
| May-2010 | Acupuncture Muscle Strength Programmes | Dr Paul Annett |
| April-2010 | Full Thickness Rotator Cuff Tears | Dr JeromeGoldberg |
| Mar-2010 | Skiing after TKR | Prof Warwick Bruce |
| Feb-2010 | Fractures of the Clavicle | Dr John Trantalis |
| Jan-2010 | Osteoarthritis of the Knee | Dr Doron Sher |
| Dec-2009 | Fifrth Metatarsal Fractures | Dr Todd Gothelf |
| Nov-2009 | Partial Rotator Cuff Tears | Dr Todd Gothelf |